Role of Putative Second Transmembrane Region of Nox2 Protein in the Structural Stability and Electron Transfer of the Phagocytic NADPH Oxidase

Flavocytochrome b(558) (cytb) of phagocytes is a heterodimeric integral membrane protein composed of two subunits, p22(phox) and gp91(phox). The latter subunit, also known as Nox2, has a cytosolic C-terminal “dehydrogenase domain” containing FAD/NADPH-binding sites. The N-terminal half of Nox2 conta...

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Main Authors: Picciocchi, Antoine, Debeurme, Franck, Beaumel, Sylvain, Dagher, Marie-Claire, Grunwald, Didier, Jesaitis, Algirdas J., Stasia, Marie-José
格式: Artigo
語言:Inglês
出版: American Society for Biochemistry and Molecular Biology 2011
主題:
Molecular Bases of Disease
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3151079/
https://ncbi.nlm.nih.gov/pubmed/21659519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.220418
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