Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase.

The phagocyte NADPH oxidase, dormant in resting cells, is activated during phagocytosis to produce superoxide, a precursor of microbicidal oxidants. The activated oxidase is a complex of membrane-integrated cytochrome b558, composed of 91-kDa (gp91phox) and 22-kDa (p22phox) subunits, and two cytosol...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Sumimoto, H, Kage, Y, Nunoi, H, Sasaki, H, Nose, T, Fukumaki, Y, Ohno, M, Minakami, S, Takeshige, K
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1994
Assuntos:	Research Article
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43991/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8202490/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.12.5345
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