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Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase.

The phagocyte NADPH oxidase, dormant in resting cells, is activated during phagocytosis to produce superoxide, a precursor of microbicidal oxidants. The activated oxidase is a complex of membrane-integrated cytochrome b558, composed of 91-kDa (gp91phox) and 22-kDa (p22phox) subunits, and two cytosol...

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Detalhes bibliográficos
Main Authors: Sumimoto, H, Kage, Y, Nunoi, H, Sasaki, H, Nose, T, Fukumaki, Y, Ohno, M, Minakami, S, Takeshige, K
Formato: Artigo
Idioma:Inglês
Publicado em: 1994
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC43991/
https://ncbi.nlm.nih.gov/pubmed/8202490
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