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Insulin signaling in retinal neurons is regulated within cholesterol-enriched membrane microdomains

Neuronal cell death is an early pathological feature of diabetic retinopathy. We showed previously that insulin receptor signaling is diminished in retinas of animal models of diabetes and that downstream Akt signaling is involved in insulin-mediated retinal neuronal survival. Therefore, further und...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Fox, Todd E., Young, Megan M., Pedersen, Michelle M., Giambuzzi-Tussey, Sarah, Kester, Mark, Gardner, Thomas W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Physiological Society 2011
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3279305/
https://ncbi.nlm.nih.gov/pubmed/21205932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpendo.00641.2010
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