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Neurotensin receptor-1 inducible palmitoylation is required for efficient receptor-mediated mitogenic-signaling within structured membrane microdomains

Neurotensin receptor-1 (NTSR-1) is a G-protein coupled receptor (GPCR) that has been recently identified as a mediator of cancer progression. NTSR-1 and its endogenous ligand, neurotensin (NTS), are co-expressed in several breast cancer cell lines and breast cancer tumor samples. Based on our previo...

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Detalhes bibliográficos
Main Authors: Heakal, Yasser, Woll, Matthew P, Fox, Todd, Seaton, Kelly, Levenson, Robert, Kester, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3219081/
https://ncbi.nlm.nih.gov/pubmed/21725197
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cbt.12.5.15984
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