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Palmitoylation is required for efficient Fas cell death signaling
Localization of the death receptor Fas to specialized membrane microdomains is crucial to Fas-mediated cell death signaling. Here, we report that the post-translational modification of Fas by palmitoylation at the membrane proximal cysteine residue in the cytoplasmic region is the targeting signal f...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1782379/ https://ncbi.nlm.nih.gov/pubmed/17159908 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.emboj.7601456 |
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