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Cholesterol‐enriched membrane rafts and insulin secretion
The failure of pancreatic β‐cells to supply insulin in quantities sufficient to maintain euglycemia is a hallmark of type 2 diabetes. Perturbation of β‐cell cholesterol homeostasis, culminating in elevated intracellular cholesterol levels, impairs insulin secretion and has therefore been proposed as...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Blackwell Publishing Ltd
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4019251/ https://ncbi.nlm.nih.gov/pubmed/24843586 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.2040-1124.2012.00200.x |
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