Hyperactivation of oxidative mitochondrial metabolism in epithelial cancer cells in situ: Visualizing the therapeutic effects of metformin in tumor tissue

We have recently proposed a new mechanism for explaining energy transfer in cancer metabolism. In this scenario, cancer cells behave as metabolic parasites, by extracting nutrients from normal host cells, such as fibroblasts, via the secretion of hydrogen peroxide as the initial trigger. Oxidative s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Whitaker-Menezes, Diana, Martinez-Outschoorn, Ubaldo E, Flomenberg, Neal, Birbe, Ruth C, Witkiewicz, Agnieszka K, Howell, Anthony, Pavlides, Stephanos, Tsirigos, Aristotelis, Ertel, Adam, Pestell, Richard G, Broda, Paolo, Minetti, Carlo, Lisanti, Michael P, Sotgia, Federica
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Landes Bioscience 2011
Pynciau:
Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272287/
https://ncbi.nlm.nih.gov/pubmed/22134189
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.23.18151
Tagiau: Ychwanegu Tag
Dim Tagiau, Byddwch y cyntaf i dagio'r cofnod hwn!

Eitemau Tebyg