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Is cancer a metabolic rebellion against host aging?: In the quest for immortality, tumor cells try to save themselves by boosting mitochondrial metabolism

Aging drives large systemic reductions in oxidative mitochondrial function, shifting the entire body metabolically toward aerobic glycolysis, a.k.a, the Warburg effect. Aging is also one of the most significant risk factors for the development of human cancers, including breast tumors. How are these...

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書誌詳細
主要な著者: Ertel, Adam, Tsirigos, Aristotelis, Whitaker-Menezes, Diana, Birbe, Ruth C, Pavlides, Stephanos, Martinez-Outschoorn, Ubaldo E, Pestell, Richard G, Howell, Anthony, Sotgia, Federica, Lisanti, Michael P
フォーマット: Artigo
言語:Inglês
出版事項: Landes Bioscience 2012
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3293377/
https://ncbi.nlm.nih.gov/pubmed/22234241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.2.19006
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