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Accelerated aging in the tumor microenvironment: Connecting aging, inflammation and cancer metabolism with personalized medicine
Cancer is thought to be a disease associated with aging. Interestingly, normal aging is driven by the production of ROS and mitochondrial oxidative stress, resulting in the cumulative accumulation of DNA damage. Here, we discuss how ROS signaling, NFκB- and HIF1-activation in the tumor micro-environ...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Landes Bioscience
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3154359/ https://ncbi.nlm.nih.gov/pubmed/21654190 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.13.16233 |
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