Cytokine production and inflammation drive autophagy in the tumor microenvironment: Role of stromal caveolin-1 as a key regulator

Recently, we proposed a new paradigm for understanding the role of the tumor microenvironment in breast cancer onset and progression. In this model, cancer cells induce oxidative stress in adjacent fibroblasts. This, in turn, results in the onset of stromal autophagy, which produces recycled nutrien...

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Bibliographic Details
Main Authors: Martinez-Outschoorn, Ubaldo E, Whitaker-Menezes, Diana, Lin, Zhao, Flomenberg, Neal, Howell, Anthony, Pestell, Richard G, Lisanti, Michael P, Sotgia, Federica
Format: Artigo
Language:Inglês
Published: Landes Bioscience 2011
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3142462/
https://ncbi.nlm.nih.gov/pubmed/21566463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.11.15674
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