Accelerated aging in the tumor microenvironment: Connecting aging, inflammation and cancer metabolism with personalized medicine

Cancer is thought to be a disease associated with aging. Interestingly, normal aging is driven by the production of ROS and mitochondrial oxidative stress, resulting in the cumulative accumulation of DNA damage. Here, we discuss how ROS signaling, NFκB- and HIF1-activation in the tumor micro-environ...

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Detaylı Bibliyografya
Asıl Yazarlar: Lisanti, Michael P, Martinez-Outschoorn, Ubaldo E, Pavlides, Stephanos, Whitaker-Menezes, Diana, Pestell, Richard G, Howell, Anthony, Sotgia, Federica
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Landes Bioscience 2011
Konular:
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Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154359/
https://ncbi.nlm.nih.gov/pubmed/21654190
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.13.16233
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