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Warburg Meets Autophagy: Cancer-Associated Fibroblasts Accelerate Tumor Growth and Metastasis via Oxidative Stress, Mitophagy, and Aerobic Glycolysis

Significance: Here, we review certain recent advances in oxidative stress and tumor metabolism, which are related to understanding the contributions of the microenvironment in promoting tumor growth and metastasis. In the early 1920s, Otto Warburg, a Nobel Laureate, formulated a hypothesis to explai...

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Dettagli Bibliografici
Autori principali: Pavlides, Stephanos, Vera, Iset, Gandara, Ricardo, Sneddon, Sharon, Pestell, Richard G., Mercier, Isabelle, Martinez-Outschoorn, Ubaldo E., Whitaker-Menezes, Diana, Howell, Anthony, Sotgia, Federica, Lisanti, Michael P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Mary Ann Liebert, Inc. 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324816/
https://ncbi.nlm.nih.gov/pubmed/21883043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.4243
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