Warburg Meets Autophagy: Cancer-Associated Fibroblasts Accelerate Tumor Growth and Metastasis via Oxidative Stress, Mitophagy, and Aerobic Glycolysis

Significance: Here, we review certain recent advances in oxidative stress and tumor metabolism, which are related to understanding the contributions of the microenvironment in promoting tumor growth and metastasis. In the early 1920s, Otto Warburg, a Nobel Laureate, formulated a hypothesis to explai...

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Detalhes bibliográficos
Main Authors: Pavlides, Stephanos, Vera, Iset, Gandara, Ricardo, Sneddon, Sharon, Pestell, Richard G., Mercier, Isabelle, Martinez-Outschoorn, Ubaldo E., Whitaker-Menezes, Diana, Howell, Anthony, Sotgia, Federica, Lisanti, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2012
Assuntos:
Forum Review Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324816/
https://ncbi.nlm.nih.gov/pubmed/21883043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.4243
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