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Warburg Meets Autophagy: Cancer-Associated Fibroblasts Accelerate Tumor Growth and Metastasis via Oxidative Stress, Mitophagy, and Aerobic Glycolysis

Significance: Here, we review certain recent advances in oxidative stress and tumor metabolism, which are related to understanding the contributions of the microenvironment in promoting tumor growth and metastasis. In the early 1920s, Otto Warburg, a Nobel Laureate, formulated a hypothesis to explai...

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Hlavní autoři: Pavlides, Stephanos, Vera, Iset, Gandara, Ricardo, Sneddon, Sharon, Pestell, Richard G., Mercier, Isabelle, Martinez-Outschoorn, Ubaldo E., Whitaker-Menezes, Diana, Howell, Anthony, Sotgia, Federica, Lisanti, Michael P.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2012
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3324816/
https://ncbi.nlm.nih.gov/pubmed/21883043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ars.2011.4243
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