Hydrogen peroxide fuels aging, inflammation, cancer metabolism and metastasis: The seed and soil also needs “fertilizer”

In 1889, Dr. Stephen Paget proposed the “seed and soil” hypothesis, which states that cancer cells (the seeds) need the proper microenvironment (the soil) for them to grow, spread and metastasize systemically. In this hypothesis, Dr. Paget rightfully recognized that the tumor microenvironment has an...

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Bibliographische Detailangaben
Hauptverfasser: Lisanti, Michael P, Martinez-Outschoorn, Ubaldo E, Lin, Zhao, Pavlides, Stephanos, Whitaker-Menezes, Diana, Pestell, Richard G, Howell, Anthony, Sotgia, Federica
Format: Artigo
Sprache:Inglês
Veröffentlicht: Landes Bioscience 2011
Schlagworte:
Perspective
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3180186/
https://ncbi.nlm.nih.gov/pubmed/21734470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.15.16870
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