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Characterization of KCNQ1 atrial fibrillation mutations reveals distinct dependence on KCNE1
The I(Ks) potassium channel, critical to control of heart electrical activity, requires assembly of α (KCNQ1) and β (KCNE1) subunits. Inherited mutations in either I(Ks) channel subunit are associated with cardiac arrhythmia syndromes. Two mutations (S140G and V141M) that cause familial atrial fibri...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Rockefeller University Press
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3269792/ https://ncbi.nlm.nih.gov/pubmed/22250012 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201110672 |
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