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KCNE1 alters the voltage sensor movements necessary to open the KCNQ1 channel gate
The delayed rectifier I(Ks) potassium channel, formed by coassembly of α- (KCNQ1) and β- (KCNE1) subunits, is essential for cardiac function. Although KCNE1 is necessary to reproduce the functional properties of the native I(Ks) channel, the mechanism(s) through which KCNE1 modulates KCNQ1 is unknow...
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| Главные авторы: | , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3012494/ https://ncbi.nlm.nih.gov/pubmed/21149716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1016300108 |
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