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Allosteric gating mechanism underlies the flexible gating of KCNQ1 potassium channels

KCNQ1 (Kv7.1) is a unique member of the superfamily of voltage-gated K(+) channels in that it displays a remarkable range of gating behaviors tuned by coassembly with different β subunits of the KCNE family of proteins. To better understand the basis for the biophysical diversity of KCNQ1 channels,...

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Detalhes bibliográficos
Main Authors: Osteen, Jeremiah D., Barro-Soria, Rene, Robey, Seth, Sampson, Kevin J., Kass, Robert S., Larsson, H. Peter
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2012
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3344993/
https://ncbi.nlm.nih.gov/pubmed/22509038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1201582109
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