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KCNE1 and KCNE3 modulate KCNQ1 channels by affecting different gating transitions
KCNE β-subunits assemble with and modulate the properties of voltage-gated K(+) channels. In the heart, KCNE1 associates with the α-subunit KCNQ1 to generate the slowly activating, voltage-dependent potassium current (I(Ks)) in the heart that controls the repolarization phase of cardiac action poten...
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| Gepubliceerd in: | Proc Natl Acad Sci U S A |
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| Hoofdauteurs: | , , , , , |
| Formaat: | Artigo |
| Taal: | Inglês |
| Gepubliceerd in: |
National Academy of Sciences
2017
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| Onderwerpen: | |
| Online toegang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5584458/ https://ncbi.nlm.nih.gov/pubmed/28808020 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710335114 |
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