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KCNE1 and KCNE3 modulate KCNQ1 channels by affecting different gating transitions

KCNE β-subunits assemble with and modulate the properties of voltage-gated K(+) channels. In the heart, KCNE1 associates with the α-subunit KCNQ1 to generate the slowly activating, voltage-dependent potassium current (I(Ks)) in the heart that controls the repolarization phase of cardiac action poten...

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Vydáno v:Proc Natl Acad Sci U S A
Hlavní autoři: Barro-Soria, Rene, Ramentol, Rosamary, Liin, Sara I., Perez, Marta E., Kass, Robert S., Larsson, H. Peter
Médium: Artigo
Jazyk:Inglês
Vydáno: National Academy of Sciences 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5584458/
https://ncbi.nlm.nih.gov/pubmed/28808020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1710335114
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