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Pharmacology of the Na(v)1.1 domain IV voltage sensor reveals coupling between inactivation gating processes
The Na(v)1.1 voltage-gated sodium channel is a critical contributor to excitability in the brain, where pathological loss of function leads to such disorders as epilepsy, Alzheimer’s disease, and autism. This voltage-gated sodium (Na(v)) channel subtype also plays an important role in mechanical pai...
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| Vydáno v: | Proc Natl Acad Sci U S A |
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| Hlavní autoři: | , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
National Academy of Sciences
2017
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5495237/ https://ncbi.nlm.nih.gov/pubmed/28607094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1621263114 |
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