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Location of KCNE1 relative to KCNQ1 in the I(KS) potassium channel by disulfide cross-linking of substituted cysteines

The cardiac-delayed rectifier K(+) current (I(KS)) is carried by a complex of KCNQ1 (Q1) subunits, containing the voltage-sensor domains and the pore, and auxiliary KCNE1 (E1) subunits, required for the characteristic I(KS) voltage dependence and kinetics. To locate the transmembrane helix of E1 (E1...

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Autores principales: Chung, David Y., Chan, Priscilla J., Bankston, John R., Yang, Lin, Liu, Guoxia, Marx, Steven O., Karlin, Arthur, Kass, Robert S.
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2009
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2630058/
https://ncbi.nlm.nih.gov/pubmed/19131515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0811897106
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