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Dynamic Partnership between KCNQ1 and KCNE1 and Influence on Cardiac I(Ks) Current Amplitude by KCNE2
Cardiac slow delayed rectifier (I(Ks)) channel is composed of KCNQ1 (pore-forming) and KCNE1 (auxiliary) subunits. Although KCNE1 is an obligate I(Ks) component that confers the uniquely slow gating kinetics, KCNE2 is also expressed in human heart. In vitro experiments suggest that KCNE2 can associa...
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| Auteurs principaux: | , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
American Society for Biochemistry and Molecular Biology
2009
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2713561/ https://ncbi.nlm.nih.gov/pubmed/19372218 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M808262200 |
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