Structure-activity relationships for allosteric NMDA receptor inhibitors based on 2-naphthoic acid

Over-activation of N-methyl-D-aspartate (NMDA) receptors is critically involved in many neurological conditions, thus there has been considerable interest in developing NMDA receptor antagonists. We have recently identified a series of naphthoic and phenanthroic acid compounds that allosterically mo...

Full description

Saved in:
Bibliographic Details
Main Authors: Costa, Blaise Mathias, Irvine, Mark W., Fang, Guangyu, Eaves, Richard J., Mayo-Martin, Maria Belen, Laube, Bodo, Jane, David E., Monaghan, Daniel T.
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269548/
https://ncbi.nlm.nih.gov/pubmed/22155206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.11.019
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items