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Pharmacological Modulation of NMDA Receptor Activity and the Advent of Negative and Positive Allosteric Modulators

The NMDA receptor (NMDAR) family of L-glutamate receptors are well known to have diverse roles in CNS function as well as in various neuropathological and psychiatric conditions. Until recently, the types of agents available to pharmacologically regulate NMDAR function have been quite limited in ter...

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Detalhes bibliográficos
Main Authors: Monaghan, Daniel T., Irvine, Mark W., Costa, Blaise Mathias, Fang, Guangyu, Jane, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3360989/
https://ncbi.nlm.nih.gov/pubmed/22269804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuint.2012.01.004
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