The NMDA receptor intracellular C-terminal domains reciprocally interact with allosteric modulators

N-Methyl-D-aspartate receptors (NMDARs) have multiple prominent roles in CNS function but their excessive or insufficient activity contributes to neuropathological/psychiatric disorders. Consequently, a variety of positive and negative allosteric modulators (PAMs and NAMs, respectively) have recentl...

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Publicado en:Biochem Pharmacol
Main Authors: Sapkota, Kiran, Dore, Kim, Tang, Kang, Irvine, Mark, Fang, Guangyu, Burnell, Erica S., Malinow, Roberto, Jane, David E., Monaghan, Daniel T.
Formato: Artigo
Idioma:Inglês
Publicado: 2018
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7058367/
https://ncbi.nlm.nih.gov/pubmed/30503374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bcp.2018.11.018
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