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Positive and Negative Allosteric Modulators of N-Methyl-D-Aspartate (NMDA) Receptors; Structure-Activity Relationships and Mechanisms of Action

Excitatory activity in the CNS is predominately mediated by L-glutamate through several families of L-glutamate neurotransmitter receptors. Of these, the N-methyl-D-aspartate receptor (NMDAR) family has many critical roles in CNS function and in various neuropathological and psychiatric conditions....

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Bibliografske podrobnosti
izdano v:J Med Chem
Main Authors: Burnell, Erica S., Irvine, Mark, Fang, Guangyu, Sapkota, Kiran, Jane, David E., Monaghan, Daniel T.
Format: Artigo
Jezik:Inglês
Izdano: 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6368479/
https://ncbi.nlm.nih.gov/pubmed/29446949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.7b01640
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