A Novel Family of Negative and Positive Allosteric Modulators of NMDA Receptors

The N-methyl-d-aspartate (NMDA) receptor family regulates various central nervous system functions, such as synaptic plasticity. However, hypo- or hyperactivation of NMDA receptors is critically involved in many neurological and psychiatric conditions, such as pain, stroke, epilepsy, neurodegenerati...

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Hlavní autoři: Costa, Blaise Mathias, Irvine, Mark W., Fang, Guangyu, Eaves, Richard J., Mayo-Martin, Marie Belen, Skifter, Donald A., Jane, David E., Monaghan, Daniel T.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Pharmacology and Experimental Therapeutics 2010
Témata:
Neuropharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2993558/
https://ncbi.nlm.nih.gov/pubmed/20858708
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.110.174144
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