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Structure-activity relationships for allosteric NMDA receptor inhibitors based on 2-naphthoic acid
Over-activation of N-methyl-D-aspartate (NMDA) receptors is critically involved in many neurological conditions, thus there has been considerable interest in developing NMDA receptor antagonists. We have recently identified a series of naphthoic and phenanthroic acid compounds that allosterically mo...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3269548/ https://ncbi.nlm.nih.gov/pubmed/22155206 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.11.019 |
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