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Structure-activity relationships for allosteric NMDA receptor inhibitors based on 2-naphthoic acid

Over-activation of N-methyl-D-aspartate (NMDA) receptors is critically involved in many neurological conditions, thus there has been considerable interest in developing NMDA receptor antagonists. We have recently identified a series of naphthoic and phenanthroic acid compounds that allosterically mo...

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Detalhes bibliográficos
Main Authors: Costa, Blaise Mathias, Irvine, Mark W., Fang, Guangyu, Eaves, Richard J., Mayo-Martin, Maria Belen, Laube, Bodo, Jane, David E., Monaghan, Daniel T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3269548/
https://ncbi.nlm.nih.gov/pubmed/22155206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuropharm.2011.11.019
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