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Synthesis of a Series of Novel 3,9-Disubstituted Phenanthrenes as Analogues of Known NMDA Receptor Allosteric Modulators

9-Substituted phenanthrene-3-carboxylic acids have been reported to have allosteric modulatory activity at the NMDA receptor. This receptor is activated by the excitatory neurotransmitter L-glutamate and has been implicated in a range of neurological disorders such as schizophrenia, epilepsy and chr...

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Detalhes bibliográficos
Publicado no:Synthesis (Stuttg)
Main Authors: Irvine, Mark W., Fang, Guangyu, Eaves, Richard, Mayo-Martin, Maria B., Burnell, Erica S., Costa, Blaise M., Culley, Georgia R., Volianskis, Arturas, Collingridge, Graham L., Monaghan, Daniel T., Jane, David E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4641328/
https://ncbi.nlm.nih.gov/pubmed/26568642
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1055/s-0034-1380114
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