Role of Human DNA Glycosylase Nei-like 2 (NEIL2) and Single Strand Break Repair Protein Polynucleotide Kinase 3′-Phosphatase in Maintenance of Mitochondrial Genome

The repair of reactive oxygen species-induced base lesions and single strand breaks (SSBs) in the nuclear genome via the base excision (BER) and SSB repair (SSBR) pathways, respectively, is well characterize, and important for maintaining genomic integrity. However, the role of mitochondrial (mt) BE...

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Detalhes bibliográficos
Main Authors: Mandal, Santi M., Hegde, Muralidhar L., Chatterjee, Arpita, Hegde, Pavana M., Szczesny, Bartosz, Banerjee, Dibyendu, Boldogh, Istvan, Gao, Rui, Falkenberg, Maria, Gustafsson, Claes M., Sarkar, Partha S., Hazra, Tapas K.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
DNA and Chromosomes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3268439/
https://ncbi.nlm.nih.gov/pubmed/22130663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.272179
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