Yüklüyor......
Inhibiting nucleation of amyloid structure in a huntingtin fragment by targeting α-helix rich oligomeric intermediates
Although oligomeric intermediates are transiently formed in almost all known amyloid assembly reactions, their mechanistic roles are poorly understood. Recently we demonstrated a critical role for the 17 amino acid N-terminal segment (htt(NT)) of huntingtin (htt) in oligomer-mediated amyloid assembl...
Kaydedildi:
| Asıl Yazarlar: | , , , , , , , , |
|---|---|
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2011
|
| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3267848/ https://ncbi.nlm.nih.gov/pubmed/22178478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.12.011 |
| Etiketler: |
Etiketle
Etiket eklenmemiş, İlk siz ekleyin!
|