ロード中...

The aggregation-enhancing Huntingtin N-terminus is helical in amyloid fibrils

The 17-residue N-terminus (htt(NT)) directly flanking the polyQ sequence in huntingtin (htt) N-terminal fragments plays a crucial role in initiating and accelerating the aggregation process that is associated with Huntington’s disease (HD) pathogenesis. Here we report on magic-angle-spinning solid s...

詳細記述

保存先:
書誌詳細
主要な著者: Sivanandam, V.N., Jayaraman, Murali, Hoop, Cody L., Kodali, Ravindra, Wetzel, Ronald, van der Wel, Patrick C.A.
フォーマット: Artigo
言語:Inglês
出版事項: 2011
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3109494/
https://ncbi.nlm.nih.gov/pubmed/21381744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja110715f
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!