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Dissociation between duration of action in the forced swim test and nicotinic acetylcholine receptor occupancy with sazetidine, varenicline, and 5-I-A85380
RATIONALE: Nicotinic acetylcholine receptor (nAChR) agonists, partial agonists and antagonists have antidepressant-like effects in rodent models and reduce symptoms of depression in humans. OBJECTIVE: The aim of this study was to determine if the β2* partial agonist sazetidine-A (sazetidine) showed...
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| Main Authors: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3266849/ https://ncbi.nlm.nih.gov/pubmed/21487659 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-011-2271-y |
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