Discovery of Isoxazole Analogs of Sazetidine-A as Selective α4β2-Nicotinic Acetylcholine Receptor (nAChR) Partial Agonists for the Treatment of Depression

Depression, a common neurological condition, is one of the leading causes of disability and suicide worldwide. Standard treatment targeting monoamine transporters selective for the neurotransmitters serotonin and noradrenalin are not able to help many patients that are poor responders. This study ad...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Liu, Jianhua, Yu, Li-Fang, Eaton, J. Brek, Caldarone, Barbara, Cavino, Katie, Ruiz, Christina, Terry, Matthew, Fedolak, Allison, Wang, Daguang, Ghavami, Afshin, Lowe, David A., Brunner, Dani, Lukas, Ronald J., Kozikowski, Alan P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3197876/
https://ncbi.nlm.nih.gov/pubmed/21905669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/jm200855b
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados