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Silencing of DLC1 Upregulates PAI-1 Expression and Reduces Migration in Normal Prostate Cells
Deleted in liver cancer 1 (DLC1) is a GTPase activating protein (GAP) domain containing tumor suppressor that localizes to focal adhesions. In cancer cells, loss of DLC1 is known to enhance cancer cell migration. However, the role of DLC1 in normal cell migration has not been well studied. Here, we...
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| Autores principales: | , , |
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| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
2011
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3262057/ https://ncbi.nlm.nih.gov/pubmed/22064653 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0450 |
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