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Silencing of DLC1 Upregulates PAI-1 Expression and Reduces Migration in Normal Prostate Cells

Deleted in liver cancer 1 (DLC1) is a GTPase activating protein (GAP) domain containing tumor suppressor that localizes to focal adhesions. In cancer cells, loss of DLC1 is known to enhance cancer cell migration. However, the role of DLC1 in normal cell migration has not been well studied. Here, we...

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Detalhes bibliográficos
Main Authors: Shih, Yi-Ping, Takada, Yoshikazu, Lo, Su Hao
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3262057/
https://ncbi.nlm.nih.gov/pubmed/22064653
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-11-0450
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