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Mutations in DLC-1's (deleted in liver cancer 1) focal adhesion targeting region attenuate their expression and function
Deleted in liver cancer-1 (DLC-1) is a RhoGAP domain containing tumor suppressor that is often down-regulated in various cancer types. Previously, we have demonstrated that DLC-1 is recruited to focal adhesions by binding to the SH2 (Src homology 2) domains of tensins and the focal adhesion localiza...
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| Autors principals: | , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2008
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2597479/ https://ncbi.nlm.nih.gov/pubmed/18829524 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2042 |
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