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Mutations in DLC-1's (deleted in liver cancer 1) focal adhesion targeting region attenuate their expression and function

Deleted in liver cancer-1 (DLC-1) is a RhoGAP domain containing tumor suppressor that is often down-regulated in various cancer types. Previously, we have demonstrated that DLC-1 is recruited to focal adhesions by binding to the SH2 (Src homology 2) domains of tensins and the focal adhesion localiza...

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Autors principals: Liao, Yi-Chun, Shih, Yi-Ping, Lo, Su Hao
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2597479/
https://ncbi.nlm.nih.gov/pubmed/18829524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-08-2042
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