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Down-regulation of DLC1 in endothelial cells compromises the angiogenesis process
DLC1 is a RhoGAP-containing tumor suppressor that inhibits angiogenesis by repressing VEGF production in epithelial cells. Here we report the roles of DLC1 in endothelial cells. Silencing of DLC1 (siDLC1) enhances cell migration but reduces tube formation activities of human umbilical vein endotheli...
Enregistré dans:
| Publié dans: | Cancer Lett |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5460982/ https://ncbi.nlm.nih.gov/pubmed/28408355 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2017.04.004 |
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