A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2

The molecular pathophysiology of myeloproliferative neoplasms (MPNs) remains poorly understood. Based on the observation that the transcription factor NF-E2 is often overexpressed in MPN patients, independent of the presence of other molecular aberrations, we generated mice expressing an NF-E2 trans...

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Bibliografiset tiedot
Päätekijät: Kaufmann, Kai B., Gründer, Albert, Hadlich, Tobias, Wehrle, Julius, Gothwal, Monika, Bogeska, Ruzhica, Seeger, Thalia S., Kayser, Sarah, Pham, Kien-Binh, Jutzi, Jonas S., Ganzenmüller, Lucas, Steinemann, Doris, Schlegelberger, Brigitte, Wagner, Julia M., Jung, Manfred, Will, Britta, Steidl, Ulrich, Aumann, Konrad, Werner, Martin, Günther, Thomas, Schüle, Roland, Rambaldi, Alessandro, Pahl, Heike L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: The Rockefeller University Press 2012
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260873/
https://ncbi.nlm.nih.gov/pubmed/22231305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110540
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