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Transcription factor nuclear factor erythroid-2 mediates expression of the cytokine interleukin 8, a known predictor of inferior outcome in patients with myeloproliferative neoplasms

The transcription factor nuclear factor erythroid-2 is over-expressed in patients with myeloproliferative neoplasms irrespective of the presence of the JAK2(V617F) mutation. Our transgenic mouse model over-expressing nuclear factor erythroid-2, which recapitulates many features of myeloproliferative...

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Autors principals: Wehrle, Julius, Seeger, Thalia S., Schwemmers, Sven, Pfeifer, Dietmar, Bulashevska, Alla, Pahl, Heike L.
Format: Artigo
Idioma:Inglês
Publicat: Ferrata Storti Foundation 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3696611/
https://ncbi.nlm.nih.gov/pubmed/23445878
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3324/haematol.2012.071183
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