Many roads lead to MPN

Por Pahl, Heike L.
Publicado em 2014

Elevated Nuclear Factor Erythroid-2 Levels Promote Epo-Independent Erythroid Maturation and Recapitulate the Hematopoietic Stem Cell and Common Myeloid Progenitor Expansion Observe...

Por Bogeska, Ruzhica, Pahl, Heike L.
Publicado em 2013

The Hen or the Egg: Inflammatory Aspects of Murine MPN Models

Por Jutzi, Jonas S., Pahl, Heike L.
Publicado no Mediators Inflamm (2015)

Clinical and hematological presentation of children and adolescents with polycythemia vera

Por Cario, Holger, McMullin, Mary Frances, Pahl, Heike L.
Publicado em 2009

NFE2 regulates transcription of multiple enzymes in the heme biosynthesis pathway

Por Rheinemann, Lara, Seeger, Thalia S., Wehrle, Julius, Pahl, Heike L.
Publicado em 2014

AML1 is overexpressed in patients with myeloproliferative neoplasms and mediates JAK2(V617F)-independent overexpression of NF-E2

Por Wang, Wei, Schwemmers, Sven, Hexner, Elizabeth O., Pahl, Heike L.
Publicado em 2010

The AML1/ETO target gene LAT2 interferes with differentiation of normal hematopoietic precursor cells

Por Essig, Aitomi, Duque-Afonso, Jesus, Schwemmers, Sven, Pahl, Heike L., Lübbert, Michael
Publicado em 2013

Proteins Encoded by the cag Pathogenicity Island of Helicobacter pylori Are Required for NF-κB Activation

Por Glocker, Erik, Lange, Christina, Covacci, Antonello, Bereswill, Stefan, Kist, Manfred, Pahl, Heike L.
Publicado em 1998

Transcription factor nuclear factor erythroid-2 mediates expression of the cytokine interleukin 8, a known predictor of inferior outcome in patients with myeloproliferative neoplas...

Por Wehrle, Julius, Seeger, Thalia S., Schwemmers, Sven, Pfeifer, Dietmar, Bulashevska, Alla, Pahl, Heike L.
Publicado em 2013

A novel role for nuclear factor-erythroid 2 in erythroid maturation by modulation of mitochondrial autophagy

Por Gothwal, Monika, Wehrle, Julius, Aumann, Konrad, Zimmermann, Vanessa, Gründer, Albert, Pahl, Heike L.
Publicado no Haematologica (2016)

JAK2(V617F)-negative ET Patients do not display constitutively active JAK/STAT signaling

Por Schwemmers, Sven, Will, Britta, Waller, Cornelius F., Abdulkarim, Khadija, Johansson, Peter, Andreasson, Björn, Pahl, Heike L.
Publicado em 2007

Krüppel-like factor 15 regulates BMPER in endothelial cells

Por Helbing, Thomas, Volkmar, Franziska, Goebel, Ulrich, Heinke, Jennifer, Diehl, Philipp, Pahl, Heike L., Bode, Christoph, Patterson, Cam, Moser, Martin
Publicado em 2010

NF-E2 Overexpression Delays Erythroid Maturation and Increases Erythrocyte Production

Por Mutschler, Manuel, Magin, Angela S., Buerge, Martina, Roelz, Roland, Schanne, Daniel H., Will, Britta, Pilz, Ingo H., Migliaccio, Anna Rita, Pahl, Heike L.
Publicado em 2009

Subcellular mislocalization of the transcription factor NF-E2 in erythroid cells discriminates prefibrotic primary myelofibrosis from essential thrombocythemia

Por Aumann, Konrad, Frey, Anna-Verena, May, Annette M., Hauschke, Dieter, Kreutz, Clemens, Marx, Jan P., Timmer, Jens, Werner, Martin, Pahl, Heike L.
Publicado em 2013

Increased leukocyte survival and accelerated onset of lymphoma in absence of MCL-1 S159-phosphorylation

Por Lindner, Silke E., Wissler, Manuela, Gründer, Albert, Aumann, Konrad, Ottina, Eleonora, Peintner, Lukas, Borner, Christoph, Charvet, Celine, Villunger, Andreas, Pahl, Heike L., Maurer, Ulrich
Publicado em 2013

Haematopoietic stem cell survival and transplantation efficacy is limited by the BH3-only proteins Bim and Bmf

Por Labi, Verena, Bertele, Daniela, Woess, Claudia, Tischner, Denise, Bock, Florian J, Schwemmers, Sven, Pahl, Heike L, Geley, Stephan, Kunze, Mirjam, Niemeyer, Charlotte M, Villunger, Andreas, Erlacher, Miriam
Publicado em 2013

Clinical and molecular characterisation of a prospectively collected cohort of children and adolescents with polycythemia vera

Por Cario, Holger, Schwarz, Klaus, Herter, Jan M., Komrska, Vladimir, McMullin, Mary F., Minkov, Milen, Niemeyer, Charlotte, Pospisilova, Dagmar, Reinhard, Harald, Debatin, Klaus-Michael, Pahl, Heike L.
Publicado em 2008

Activation of cellular death programs associated with immunosenescence-like phenotype in TPPII knockout mice

Por Huai, Jisen, Firat, Elke, Nil, Ahmed, Million, Daniele, Gaedicke, Simone, Kanzler, Benoit, Freudenberg, Marina, van Endert, Peter, Kohler, Gabriele, Pahl, Heike L., Aichele, Peter, Eichmann, Klaus, Niedermann, Gabriele
Publicado em 2008

JAK2 haplotype is a major risk factor for the development of myeloproliferative neoplasms

Por Jones, Amy V, Chase, Andrew, Silver, Richard T, Oscier, David, Zoi, Katerina, Wang, Y Lynn, Cario, Holger, Pahl, Heike L, Collins, Andrew, Reiter, Andreas, Grand, Francis, Cross, Nicholas C P
Publicado em 2009

MPN patients harbor recurrent truncating mutations in transcription factor NF-E2

Por Jutzi, Jonas S., Bogeska, Ruzhica, Nikoloski, Gorica, Schmid, Corina A., Seeger, Thalia S., Stegelmann, Frank, Schwemmers, Sven, Gründer, Albert, Peeken, Jan C., Gothwal, Monika, Wehrle, Julius, Aumann, Konrad, Hamdi, Kamar, Dierks, Christine, Wang, Wei, Döhner, Konstanze, Jansen, Joop H., Pahl, Heike L.
Publicado em 2013