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The AML1/ETO target gene LAT2 interferes with differentiation of normal hematopoietic precursor cells

The adaptor protein linker activator of T-cells 2 (LAT2) is a known AML1/ETO target gene whose function during normal hematopoiesis is unknown. We addressed the role of LAT2 during erythroid and myeloid differentiation of normal human CD34+ hematopoietic cells. LAT2 is expressed at low levels in CD3...

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Autori principali: Essig, Aitomi, Duque-Afonso, Jesus, Schwemmers, Sven, Pahl, Heike L., Lübbert, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4135084/
https://ncbi.nlm.nih.gov/pubmed/24456692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.leukres.2013.12.014
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