Epigenetic regulation of NFE2 overexpression in myeloproliferative neoplasms

The transcription factor “nuclear factor erythroid 2” (NFE2) is overexpressed in the majority of patients with myeloproliferative neoplasms (MPNs). In murine models, elevated NFE2 levels cause an MPN phenotype with spontaneous leukemic transformation. However, both the molecular mechanisms leading t...

詳細記述

保存先:
書誌詳細
出版年:Blood
主要な著者: Peeken, Jan C., Jutzi, Jonas S., Wehrle, Julius, Koellerer, Christoph, Staehle, Hans F., Becker, Heiko, Schoenwandt, Elias, Seeger, Thalia S., Schanne, Daniel H., Gothwal, Monika, Ott, Christopher J., Gründer, Albert, Pahl, Heike L.
フォーマット: Artigo
言語:Inglês
出版事項: American Society of Hematology 2018
主題:
Myeloid Neoplasia
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5934799/
https://ncbi.nlm.nih.gov/pubmed/29519804
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-10-810622
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料