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A novel murine model of myeloproliferative disorders generated by overexpression of the transcription factor NF-E2

The molecular pathophysiology of myeloproliferative neoplasms (MPNs) remains poorly understood. Based on the observation that the transcription factor NF-E2 is often overexpressed in MPN patients, independent of the presence of other molecular aberrations, we generated mice expressing an NF-E2 trans...

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主要な著者: Kaufmann, Kai B., Gründer, Albert, Hadlich, Tobias, Wehrle, Julius, Gothwal, Monika, Bogeska, Ruzhica, Seeger, Thalia S., Kayser, Sarah, Pham, Kien-Binh, Jutzi, Jonas S., Ganzenmüller, Lucas, Steinemann, Doris, Schlegelberger, Brigitte, Wagner, Julia M., Jung, Manfred, Will, Britta, Steidl, Ulrich, Aumann, Konrad, Werner, Martin, Günther, Thomas, Schüle, Roland, Rambaldi, Alessandro, Pahl, Heike L.
フォーマット: Artigo
言語:Inglês
出版事項: The Rockefeller University Press 2012
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3260873/
https://ncbi.nlm.nih.gov/pubmed/22231305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20110540
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