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Metal Ion Substrate Inhibition of Ferrochelatase
Ferrochelatase catalyzes the insertion of ferrous iron into protoporphyrin IX to form heme. Robust kinetic analyses of the reaction mechanism are complicated by the instability of ferrous iron in aqueous solution, particularly at alkaline pH values. At pH 7.00 the half-life for spontaneous oxidation...
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| Main Authors: | , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
American Society for Biochemistry and Molecular Biology
2008
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3259753/ https://ncbi.nlm.nih.gov/pubmed/18593702 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803372200 |
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