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Ferrochelatase π-Helix: Implications from Examining the Role of the Conserved π-Helix Glutamates in Porphyrin Metalation and Product Release
Protoporphyrin ferrochelatase catalyzes the insertion of Fe(2+) into protoporphyrin IX to form heme. To determine whether a conserved, active site π-helix contributes to the translocation of the metal ion substrate to the ferrochelatase-bound porphyrin substrate, the invariant π-helix glutamates wer...
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| Publicado no: | Arch Biochem Biophys |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5880697/ https://ncbi.nlm.nih.gov/pubmed/29481781 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2018.02.015 |
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