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Metal Ion Substrate Inhibition of Ferrochelatase

Ferrochelatase catalyzes the insertion of ferrous iron into protoporphyrin IX to form heme. Robust kinetic analyses of the reaction mechanism are complicated by the instability of ferrous iron in aqueous solution, particularly at alkaline pH values. At pH 7.00 the half-life for spontaneous oxidation...

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Detalles Bibliográficos
Autores principales: Hunter, Gregory A., Sampson, Matthew P., Ferreira, Gloria C.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2008
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259753/
https://ncbi.nlm.nih.gov/pubmed/18593702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M803372200
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