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Enantioselective Aldehyde α-Nitroalkylation via Oxidative Organocatalysis

[Image: see text] The first enantioselective organocatalytic α-nitroalkylation of aldehydes has been accomplished. The aforementioned process involves the oxidative coupling of an enamine intermediate, generated transiently via condensation of an amine catalyst with an aldehyde, with a silyl nitrona...

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Autori principali: Wilson, Jonathan E., Casarez, Anthony D., MacMillan, David W. C.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2009
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259685/
https://ncbi.nlm.nih.gov/pubmed/19627154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja904504j
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