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Enantioselective Aldehyde α-Nitroalkylation via Oxidative Organocatalysis

[Image: see text] The first enantioselective organocatalytic α-nitroalkylation of aldehydes has been accomplished. The aforementioned process involves the oxidative coupling of an enamine intermediate, generated transiently via condensation of an amine catalyst with an aldehyde, with a silyl nitrona...

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Bibliographic Details
Main Authors: Wilson, Jonathan E., Casarez, Anthony D., MacMillan, David W. C.
Format: Artigo
Language:Inglês
Published: 2009
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3259685/
https://ncbi.nlm.nih.gov/pubmed/19627154
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja904504j
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