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The Productive Merger of Iodonium Salts and Organocatalysis. A Non-Photolytic Approach to the Enantioselective α-Trifluoromethylation of Aldehydes

[Image: see text] An enantioselective organocatalytic α-trifluoromethylation of aldehydes has been accomplished using a commercially available, electrophilic trifluoromethyl source. The merging of Lewis acid and organocatalysis provides a new strategy for the enantioselective construction of trifluo...

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Bibliographic Details
Main Authors: Allen, Anna E., MacMillan, David W. C.
Format: Artigo
Language:Inglês
Published: 2010
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2880471/
https://ncbi.nlm.nih.gov/pubmed/20297822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja100748y
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